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Dr. Ronald Hoffman

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Dr. Ronald Hoffman Offers "18 Supplements That May Stave Off Alzheimer’s"

New York, NY, August 20, 2014 --( Leading New York City-based complementary medical practitioner Dr. Ronald Hoffman (, head of the Hoffman Center in Manhattan and a nationally syndicated radio host, has good news for people concerned about Alzheimer’s or who have loved ones suffering from the disease but who may be wary of taking conventional medication: There are supplements you can take to help ward off its effects. (For the complete article, click here.)

According to Dr. Hoffman, Alzheimer’s disease affects 5.5 million people, and with 10,000 Baby Boomers hitting that risk period every day that number is only expected to grow and could reach 14 million by 2050 if a solution cannot be found. “This unsustainable level of disability will sink our health care system and hobble our economy,” says Dr. Hoffman.

Conventional medicine may not offer viable options for treatment. “A new study from the Cleveland Clinic has revealed that 96.6 percent of Alzheimer’s drug trials are unsuccessful!” says Dr. Hoffman. “Of 244 drugs tested from 2002-2012, only one drug was a success—and a vary partial one at that, with only temporary small benefits and no impact on the ultimate course of the disease, and with side effects to boot!”

The good news is that there are a variety of supplements you can take to help prevent this cognitive decline. A few of Dr. Hoffman’s favorites:

DHA-rich fish oil: “Fish oil fluidizes the membranes in the brain, makes them less stiff and more readily responsive,” says Dr. Hoffman. “But in particular, DHA seems to be the business end of the fish oil that is helpful for staving off cognitive decline.”

DHEA: “DHEA works as a good antidepressant in older individuals,” says Dr. Hoffman. “It has a mood-elevating effect. It is slightly anabolic so it helps to maintain muscle mass and may encourage bone strength but it also may have a good effect on cognition and mental function. It seems to be sort of an energizer for the body and brain.”

Phosphatidylserine: “Easy way to remember that it has something to do with memory is because of its abbreviation, which is ‘P.S.’ as in ‘P.S., I forgot to tell you,’” says Dr. Hoffman of this supplement. “ Phosphatidylserine is a normal component of cell membranes. If you look at cell membranes and you analyze them, they have a very high content of phosphatidylserine. One thought is that in neurodegenerative disease, the membranes deteriorate so by supplying patients with Alzheimer’s phosphatidylserine, you may see some benefit.”

Ginkgo: “Can’t forget ginkgo when we’re talking about memory and cognitive decline,” says Dr. Hoffman. “I tell patients to take as many six of them a day.”

Melatonin: “Melatonin has a reputation of enhancing sleep and that may be the basis of its action against Alzheimer’s disease, because better sleep leads to a reduction in the risk of cognitive decline,” says Dr. Hoffman. “But also there is some separate evidence for melatonin being a potent antioxidant, and melatonin may protect neuronal cells from damage.” He adds that melatonin also may help those suffering from a condition called “sundowning,” where patients with dementia get extra agitated and anxious in the late afternoon or evening.

Vitamin D: “It’s not clear that vitamin D makes you smarter, but vitamin D can affect mood and some studies suggest that it may improve cognition as well,” says Dr. Hoffman.

Huperzine A: Derived from Chinese club moss and shown to be an acetylcholinesterase inhibitor (as are many of the drugs used to treat Alzheimer’s), Huperzine A has been used as a prescription drug in China since the 1990s. “A dose of 200 micrograms twice daily produced measurable improvements in memory, cognitive function and behavioral factors in 58 percent of Alzheimer’s patients,” says Dr. Hoffman, “so that’s a good one to employ.”

To read the full article, and for more tips about health and wellness from Dr. Hoffman and his complementary contemporaries, visit his newly relaunched website at For more comprehensive services, you also can make an appointment at the Hoffman Center (212-779-1744) or visit the Hoffman Center Store online.
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