Kubtec: Advances in BMD Research Give Osteoporosis Sufferers Hope
A study published by the National Academy of Sciences regarding cell therapy, which expanded on prior research about genetically modified hematopoietic stem cells (HSCs), has identified a growth factor which causes a 45% increase in bone strength in mice.
This development gives hope to the 75 million people currently affected by osteoporosis in Europe, USA and Japan. Osteoporosis causes “an estimated two million broken bones each year and often results in immobility, pain, placement in a nursing home, isolation and other health problems,” said Amy Porter, executive director and CEO of the National Osteoporosis Foundations (NOF), and accounts for longer hospital stays than other diseases, such as diabetes, myocardial infarction and breast cancer.
Research into Bone Mineral Density (BMD), which aids treatment in humans, often relies on high resolution X-ray imaging systems that measure BMD in mice. One system, the Kubtec DIGIMUS® System has made strides in the area of BMD analysis by providing improved imaging and shorter calibration times. The high resolution image acquisition and BMD calculation, which can be completed in seconds, minimizes the radiation dose administered to subjects and can be normalized and compared with traditional BMD system results.
Dr. Meghan McGee-Lawrence, Assistant Professor of Cellular Biology and Anatomy at Georgia Regents University, who studies BMD recently stated, “I have been very pleased with the DIGIMUS® System, which I have been using for approximately one year. The system clearly shows in vivo changes in BMD that we have verified ex vivo by other methods (e.g., microCT), such as a decrease in BMD in the femur and lumbar vertebrae in aged as compared to young animals. We have found that we get accurate data whether we analyze whole mice or isolated bone tissues. So far, we have used it to quantify BMD in tissues from mice, rats, fish, and humans.”
The DIGIMUS® System is compact and self-contained, and adapts easily to either a bench-top or a portable cart.
The NAS study may enable medical researchers to find ways to halt bone resorption and generate new bone material, erecting a road block to osteoporosis, which causes more than 8.9 million fractures annually. In turn, this therapy could revitalize bone growth and reverse osteoporosis trends, facilitating the reversal to original density levels.
For more information about the Kubtec DIGIMUS® System, visit kubtec.com.
Kubtec, a registered trademark of KUB Technologies, Inc., develops and manufactures cutting edge digital X-ray systems for clinical and non-clinical applications, including low-dose neonatal imaging, specimen radiography, scientific research, forensic analysis, non-destructive testing, irradiation and more. Kubtec is ISO 9001 and ISO 13485 certified and complies with U.S., Canadian, and European requirements for radiation safety. Systems and manufacturer-trained support is available worldwide.