Custom Sensors & Technology to Present Bin Blending and API Concentration Applications During Natoli Workshop on Challenges in Tablet Manufacturing and QA/QC

Fenton, MO, July 07, 2010 --( Custom Sensors & Technology will be presenting the LIF Sensor as a PAT tool used for bin blend uniformity, API concentration, and cleaning validation during the technical training workshop “Challenges in Tablet Manufacturing and QA/QC” to be held at Natoli on August 10-12th, 2010.

The training workshop is geared towards a magnitude of individuals; anyone involved in the manufacture or quality control of pharmaceuticals would benefit from the training. During the workshop the presenters strive to provide a basic understanding of a variety of topics including: manufacture and operations during pharmaceutical production, blend uniformity, process analytical technology (PAT), quality assurance and quality control (QA/QC), tablet characteristics, bioavailability and bioequivalence, as well as tablet presses, punches and dies. Speakers will include Dr. Adel Sakr, Emeritus Professor of Industrial Pharmacy and Pharmaceutics, and Director of the Industrial Pharmacy Graduate Program at the College of Pharmacy, University of Cincinnati Medical Center. As well as Mr. Dale Natoli, Mr. Doug Kirsch, and Mr. Dave Perry representing Natoli Engineering Company with collective industry experience in excess of 100 years. Also presenting will be Custom Sensors & Technology’s Crystal Dixon, head of the Research & Development lab who has been a key contributor to the development of the LIF Sensor.

As a valuable new Process Analytical Technology (PAT) the LIF Sensor enables manufacturers to build quality into the process, utilizing QbD to the fullest extent. Along with quality comes a decrease in product waste, reduced labor, and less equipment needed making the LIF an economically attractive solution for all fluorescence applications.

Features of the LIF Sensor include dynamic control to provide tailored analytical versatility via UV-Vis LED array technologies; integrated excitation referencing on each diode; small, light weight and self-contained form factor “sensor” device; versatile onboard hot swappable communication options and powering options, both AC and battery; optical configurations suitable for solid state detection (e.g., powders) with alternative schemes for liquids and gases; various smart sensing and diagnostics features for real-time detection assurance; open communication standard for efficient automation controls integration via OPC; solid state device for optimal robustness; and an onboard accelerometer for mobile applications such as pharmaceutical final drug product tumble blending. These comprehensive sensor novelties afford reliable monitoring for robust process control.

About CST
Custom Sensors & Technology is a full service provider. With 30 years of experience CST supplies the latest in front surface fluorescence sensing, photometric transmitters, fiber optic probes and flow cells, oxygen transmitters, sample handling systems, and services including: application engineering, commissioning and start-ups, product validation, factory acceptance testing, IOQ documentation, process stream GAP Analysis, and in-house repair. Sensors can be applied to several real-time analytical problems such as: *end-point detection for powder blending *cleaning validation *security/surveillance *color measurement *protein purity *total cell density *viable cell growth *scale *biofilm *corrosion *organics in water. For more information, visit

Custom Sensors & Technology
Sara Mohre