PR.com: Business Directory, Press Releases, Jobs, Products, Services, Articles
 
Businesses Articles Press Releases Follow @PRcom
Press Release Pricing | News by Category | News by Country | News by US Region | Recent News | PR.com News on Your Site
 

Press Releases

 
GTCbio

Press Release


Receive press releases from GTCbio: By Email RSS Feeds:

Jeremy Barton, VP at Biogen Idec to Speak at Cancer Drugs Conference on Jan 27-28 2011 San Diego, CA


Monrovia, CA, November 25, 2010 --(PR.com)-- Jeremy Barton, VP of Oncology at Biogen Idec will be the keynote presenter on “Targeted Drug Delivery: How Far from the Bulls Eye?” at GTCbio’s Cancer Drugs Research & Development Conference on January 27-28, 2011 in San Diego, CA.

Dr. Barton will address why the narrow therapeutic window of most cytotoxic drugs has limited their benefit in the clinic and normal tissue toxicity constrains the dose that can safely be administered. Linkage of a toxin to an antibody whose target may be an internalizing tumor specific antigen has the potential to achieve tumor selectivity relative to normal tissue and thereby improve the efficacy of the drug. The last 20 years have seen dramatic advances in the technologies which are used to construct such antibody drug conjugates (ADC) and there has been recent validation in the clinic of two different linkers (which bind the toxin to the antibody) and for two different toxins. This presentation will summarize the desired properties of an ADC and will show how the technological advances have contributed to the current success of such molecules. Clinical data from the two lead candidates will be presented and future advances and challenges will be discussed.

###
Contact Information
GTCbio
David Stoops
626-256-6405
Contact
http://www.gtcbio.com
GTCbio, 434 W. Foothill Blvd. Monrovia, CA 91016 fax: (626) 256-6460 email: infogtcbio@gtcbio.com

Click here to view the list of recent Press Releases from GTCbio
Promote Your Business