San Jose, CA, August 03, 2011 --(PR.com
)-- Anti-Desmoglein 3 (Dsg3) antibody (catalog # 603-810)
Desmogleins are calcium-binding transmembrane glycoproteins, members of the desmosomal cadherins that provide adhesive integrity to desmosomes between adjoining keratinocytes; They consist of proteins Dsg1, Dsg2, Dsg3, and Dsg4. Dsg3 is distributed primarily in the deeper epidermis, whereas Dsg1is localized to the superficial epidermis.
Desmoglein 3 protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris and plays important roles in human squamous cell cancer. The level of Dsg3 can be used as a read-out of pathogenic changes.
Anti-Desmoglein 3 (Dsg3) antibody (catalog # 603-810) has been validated for use in Western blot, and immunohistochemistry on paraffin-embedded human sections.
AbboMax is a biotechnology company headquartered in San Jose, California, USA. The company offers innovative primary and secondary antibodies, antibody reagents, assay kits, and liposome reagents, as well as custom services.
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