MoBiTec GmbH, Germany, Offers a New Photoconvertible and Photoactivatible Fluorescent Protein Suitable for High-Resolution Microscopy: mIrisFP

Goettingen, Germany, February 29, 2012 --(PR.com)-- Fluorescence microscopy is an integral part of routine diagnostics and fundamental medical and biological research. In order to obtain accurate results from imaging applications, it is essential to maximize the potential of the optical system.

Now MoBiTec offers mIrisFP, a photoactivatable fluorescent protein that combines irreversible photoconversion from a green- to a red-emitting form with reversible photo-switching between a fluorescent and a non-fluorescent state in both forms. mIrisFP is a monomeric variant. mIrisFP multiple photo-activation modes can be used for pulse-chase experiments combined with subdiffraction-resolution imaging in living cells by using dual-color photo-activation localization microscopy (PALM).

Monomeric mIrisFP has excellent properties as a genetically encoded fluorescence marker. mIrisFP fluorescence can be reversibly switched on and off (useful for high-resolution microscopy, PALM), but also allows for the non-reversible photo-conversion from green to red (useful for dynamic measurements in living cells). The dual photo-activation capability of mIrisFP offers enhanced flexibility and also enables the combination of pulse-chase experiments with super-resolution imaging.

For details please see:
http://www.mobitec.de/int/products/bio/07_fluores_tec/index.php?fluorprot.html

About MoBiTec GmbH
MoBiTec GmbH (Goettingen, Germany) is a privately held company (founded in 1987) that offers research tools for molecular and cell biology. Products include two- & one-hybrid systems for in vivo detection of molecular interactions, Lambda PS genomic libraries, DNA vectors for cloning and expression, kits for expression and purification of recombinant proteins, cell transfection reagents and cell culture tools, immobilized and soluble enzymes, diverse products for genomics and proteomics research, numerous antibodies and recombinant proteins, superior fluorescence reagents and kits, affinity chromatography products, as well as general laboratory equipment, e.g. plastic columns for centrifugation or affinity applications. In parallel to its own product lines, MoBiTec distributes products from several international companies in Germany. MoBiTec products are distributed worldwide, in Germany from their home office, in other countries by distributors.

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