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MoBiTec GmbH

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MoBiTec GmbH

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AmoyDx, Supplier of MoBiTec, Germany, Introduces System for Extraction of Circulating DNA from NSCLC (Non-Small Cell Lung Cancer) Patients

Circulating cell-free DNA is an important emerging biomarker in cancer diagnostics as well as a non-invasive diagnostic solution for a wide range of clinical disorders. The AmoyDx kit is specially designed for effective isolation and purification of DNA from peripheral blood (serum or plasma) and pleural effusion. The purified DNA is suitable for downstream applications such as real-time quantitative PCR (qPCR).

Goettingen, Germany, June 26, 2015 --( The reliable detection of epidermal growth factor receptor (EGFR) mutations in advanced non-small cell lung cancer (NSCLC) has provided many patients with EGFR mutation-positive disease with the opportunity to receive optimal, targeted treatments. Tumor tissue is regarded as the preferred standard sample type for EGFR mutation analysis. However, for many patients this sample type is not available in sufficient amounts.

Therefore, usage of other sample types for EGFR mutation analysis is taken into consideration. The aim is to identify the molecular characteristics of tumors from patients lacking sufficient tumor tissue samples. An alternative sample type is circulating-free tumor DNA (ctDNA), which is obtainable by less invasive methods to detect tumor DNA such as plasma or serum samples.

Amoy Diagnostics' Circulating DNA kit for purification of DNA from pleural effusion, serum, or plasma is an upgraded version of their Serum/Plasma Cell-free DNA kit. The extracted CtDNA can be used for EGFR blood testing and other analyses.

Amoy Diagostics (AmoyDx), China, is a leading provider of cancer-related real time PCR diagnostic kits. The assays are based on a proprietary real-time PCR technology called “ADx-ARMS”. They have outstanding sensitivity (1%) and accuracy (99%). Amongst others, the company supplies EGFR tests to AstraZeneca in China, and also supplies ROS1 tests for pivotal clinical trials of Pfizer´s crizotinib in China, Korea, and Japan.

All AmoyDx products are developed in ISO-13485 certified laboratories and assembled in a GMP-compliant manufacturing plant. In 2014 MoBiTec GmbH, Germany, signed a distribution agreement with AmoyDx for the German market.

About MoBiTec GmbH

MoBiTec GmbH (Goettingen, Germany) is a privately held company (founded in 1987) that offers research tools for molecular and cell biology. Products include DNA vectors for cloning and expression, cell transfection reagents and cell culture tools, immobilized and soluble enzymes, products for genomics and proteomics research, numerous antibodies and recombinant proteins, superior fluorescence reagents and kits, affinity chromatography products, as well as general laboratory equipment.

In parallel to its own product lines, MoBiTec distributes products from international companies in Germany. MoBiTec products are distributed worldwide, in Germany from their home office, in other countries by distributors.
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MoBiTec GmbH
Arne Schulz

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