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The Importance of in Vitro Discussed at ADMET 2016

SMi reports: The importance of in vitro is just one of the key topics to be discussed at SMiís 11th annual ADMET conference which will return to London on the 13th-14th June 2016.

London, United Kingdom, April 29, 2016 --( "According to the popular notion among various toxicologists, in-vitro toxicity testing methods are more useful, efficient, and less time-consuming compared to toxicology studies...Transparency Market Research (TMR) has recently published a research study on the global in-vitro toxicity testing market. The report estimates this market to rise at a CAGR of 15.30% over the period from 2012 to 2018 and reach US$4.1 bn. North America led the overall market with a share of approximately 40% in 2010, attaining a value of US$526.9 mn. Analysts project this regional market to retain its leadership during the forecast period." *(Source)

On Day One of the conference hear from Genentech (based in North America, the region with the highest market share in the in vitro market) and Imperial College London as they discuss the importance of in vitro methods of prediction.

Titled ‘Humanized Animal Models – Potential Tools for the Study of Drug Transporters’, Laurent Salphati, Senior Scientist, Drug Metabolism and Pharmacokinetics from Genentech will be discussing: Uses and limitations of in vitro transporter assays in the predictions of drug disposition and DDIs as well as humanised models available and characterisations. Laurent will also present a case study on translation to human and limitations of humanized models for drug disposition and DDI predictions.

Ian Wilson, Chair, Drug Metabolism and Molecular Toxicology from Imperial College London will present on ‘Better Models for Understanding, Predicting and Avoiding Drug Induced Liver Injury’. His session will touch upon: how unexpected hepatotoxicity remains a significant cause of drug failure and withdrawal; how the prevention of DILI requires better in vitro, in vivo and in silico methods of prediction as well as how improved understanding of the mechanisms of DILI is leading the development of new model systems

To view the full two day programme with all speakers and their topics, visit the event website on

The final early bird will expire on the 29th of April, saving you £200. There is limited availability, so registration is encouraged to take place as soon as possible to ensure you secure your place.

ADMET 2016 is sponsored by Corning and Sekisui XenoTech.

For sponsorship enquiries, contact Alia Malick on +44 (0) 207 827 6168 or

For delegate enquiries, contact Matthew Apps on +44 (0) 207 827 6093 or

For media enquiries, contact Zoe Gale on +44 (0) 207 827 6132 or

11th annual ADMET conference and exhibition
13-14 June 2016
London, UK
Contact e-mail:
Contact tel: +44 (0) 207 827 6093

About SMi Group: Established since 1993, the SMi Group is a global event-production company that specializes in Business-to-Business Conferences, Workshops, Masterclasses and online Communities. We create and deliver events in the Defence, Security, Energy, Utilities, Finance and Pharmaceutical industries. We pride ourselves on having access to the world’s most forward thinking opinion leaders and visionaries, allowing us to bring our communities together to Learn, Engage, Share and Network. More information can be found at
Contact Information
SMi Group
Zoe Gale
+44 (0) 207 827 6093

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