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AdvantaPure(R) Offers a New White Paper Focusing on Molded Tubing Connections; Illustrates the Risks and Expenses of Fluid Leaks in Biopharma Manufacturing Operations

Immediately available from high purity tubing manufacturer AdvantaPure is a report titled “How Molded Manifold Assemblies Prevent Leaks and Costly Consequences.” It addresses the risks and costs associated with tubing-to-fitting connection leaks and presents a solution, namely the use of molded connections. The white paper shows how critical leak risk becomes based on the number of connections in a manifold assembly. Additional white papers are available as well.

Southampton, PA, June 16, 2016 --( AdvantaPure has introduced a white paper that compares the uncertainty of tube sets made with barbed fittings to assemblies manufactured using leak-proof molded connections. Titled "How Molded Manifold Assemblies Prevent Leaks and Costly Consequences," the report describes how leak risks increase with each additional barbed fitting connection in an assembly and offers a solution to reduce that risk.

Moving fluid from point A to point B typically involves a number of tubing-to-fitting connections, along with components such as filters, sampling bags and bottles, all of which require cable ties for secure attachment. When connections leak, the result can involve contamination, production delays and lost income – even into the range of millions of dollars. By incorporating molded tubing connections, the risk of leaks is greatly reduced and the success rate of maintaining sterile pharma and biopharma products is increased.

The white paper explains the challenges involving a sterile fluid flow system, such as flow disruptions, meeting strict governing-association requirements, minimizing cleaning and validation requirements, and maintaining operator safety. It examines how each individual barbed connection in a tube set puts the entire fluid transfer process at risk and how much that risk rises based on the total number of connections in an assembly.

Solutions to the problem are also presented in the paper and include suggestions to replace traditional barbed fittings and cable ties with leak-proof molded connections. These types of connections offer smooth, crevice-free inner surfaces and eliminate cable ties, which can puncture components like bags.

"How Molded Manifold Assemblies Prevent Leaks and Costly Consequences" includes photographs and illustrations for easy visual explanations of the situations described. Other white papers focusing on Single-Use tubing, closures and stopper systems, and clean room fluid transfer options are also available.

For a copy of the white paper, visit or contact the AdvantaPure team by phone at 888-755-4370 or 215-526-2151; e-mail:; fax: 888-258-4293 or 215-526-2167 or at 145 James Way, Southampton, PA 18966.

About AdvantaPure and NewAge(R) Industries
The AdvantaPure division of NewAge Industries is ISO 9001:2008 certified and specializes in high purity tubing, hose, single use systems, manifolds, and other molded components for the pharmaceutical, biomedical, food, beverage, and cosmetic industries. All products are manufactured, stored, and shipped using the cleanest methods possible to ensure unsurpassed product purity.

In business since 1954, NewAge Industries manufactures plastic and rubber tubing in both reinforced and unreinforced styles. The company offers one of the broadest product lines of tubing and fittings in the U.S., provides extensive custom extrusion and fabrication capabilities, and services customers worldwide. Automated product identification systems, including gamma-stable RFID tags and labels, are offered by NewAge’s Verigenics(R) division. In 2006, NewAge initiated an ESOP (Employee Stock Ownership Plan) for the benefit of both its employees and customers.

NewAge Industries AdvantaPure(R), Verigenics(R), and NewAge(R) are registered trademarks of NewAge(R) Industries, Inc.
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