Palo Alto Facial Plastic Surgeon Helps Launch Galderma’s Refyne and Defyne Dermal Fillers

Palto Alto, CA, April 14, 2017 --( The newest additions to the Restylane family of products help treat nasolabial folds or “laugh lines.”

Dr. Jill Hessler, a facial plastic surgeon based in Palo Alto, Calif., recently helped spearhead the launch of two of Galderma’s newest injectable fillers. Restylane Refyne and Defyne were introduced at a national sales meeting in Dallas, where Dr. Hessler trained fellow physicians to use the wrinkle reducing products.

In December 2016, the FDA announced its approval of Refyne and Defyne for the treatment of moderate to severe nasolabial folds, or “laugh lines,” in patients over the age of 21.

Prior to the U.S.’s approval, Dr. Hessler acquired experience injecting the fillers in Canada. Because of her expertise, Galderma invited her to help lead the U.S. launch. Dr. Hessler was also one of the first physicians in the country to receive the fillers at her Palo Alto practice, and is excited to offer them to patients looking for subtle anti-aging effects.

The results of two pivotal clinical studies with Refyne and Defyne were promising, with the fillers demonstrating noticeable improvement after only six weeks. The fillers were shown to be effective at diminishing lines and wrinkles for up to one year.

Galderma believes that with the addition of these two brands, the Restylane family now offers the widest range of hyaluronic acid-based fillers in the country.

Specially Designed with XpresHAn Technology
Restylane Refyne and Defyne are the first of a new generation of dermal fillers manufactured with XpresHAn technology. This technology creates a smooth injectable gel for wrinkle reduction results that look more natural. Thanks to XpresHAn technology, Refyne and Defyne offer a range of flexibility and support to accommodate the diverse needs of patients.

Refyne is formulated for patients that want to subtly fill in moderate wrinkles, whereas Defyne is formulated for patients that want to treat deeper lines. Cumulatively, the fillers provide a wide range of results while helping patients maintain their normal facial expressions.

Individuals seeking treatment with Restylane Refyne or Defyne in Palo Alto are encouraged to contact Dr. Hessler by calling (650) 799-9009.

About Dr. Jill Hessler
Jill Hessler, M.D., is an award-winning facial plastic surgeon serving Palo Alto, San Jose and the entire Bay Area. Double board certified in facial plastic surgery and otolaryngology and head and neck surgery, Dr. Hessler’s focus is to reverse noticeable signs of facial aging through a range of state-of-the-art surgical and non-surgical treatments. Because of her unique experience and expertise, Dr. Hessler is a leader in her field and frequently asked to train fellow surgeons nationwide.

Dr. Hessler trained in otolaryngology and head and neck surgery at Washington University, and was selected for a facial plastic and reconstructive surgery fellowship at the University of Michigan. She later returned to Washington University to serve as a faculty member, and currently holds an adjunct teaching appointment at Stanford University.


Dr. Jill Hessler
(650) 799-9009
Jill Hessler MD
Jill Hessler