Signet Announces Acquisition of a New Medical Device to Prevent Amputations

New medical device, named the ConnREAP™, will enable physicians - for the first time - to gain optimal access to leg arteries to restore blood flow and prevent amputations.

Colorado Springs, CO, January 25, 2019 --( Signet Medical Solutions, A Signet International Holdings, Inc.’s (OTC: SIGN) subsidiary, announced that Signet’s Board of Directors voted unanimously to purchase all rights and title to a revolutionary medical device from POLR Angioscience, LLC to prevent amputations.

The device, which will be offered worldwide as a 5-piece disposable kit, will enable physicians - for the first time - to gain optimal access to the leg arteries and facilitate the best use of catheter and balloon equipment to restore blood flow and prevent amputations. According to independent studies, this device will substantially increase the rate of limb salvage. Tens of thousands of limbs could be saved per year in the USA alone.

“We have trademarked our device ConnREAP,” says Mr. Ernest Letiziano, CEO of Signet. “Its inventor, Dr. John Conn, is a vascular surgeon trained at Emory University. He has utilized the device to successfully, consistently overcome severe challenges in reaching and correcting complex blockages in the leg arteries.”

The pain and disability caused by narrowed leg arteries often ends tragically in amputation, and the technical difficulties conquered by the device allow more surgeons to restore effective blood flow. A huge and growing vulnerable population is at risk for limb loss because of aging, diabetes, and hypertension. They can benefit by this device which simplifies access to correcting the root cause: the bulky yellowish build-up of plaque in arteries.

A multinational independent research clinic spent more than a year investigating and reporting on the device. The results were positive and encouraging, with the recommendation to proceed with development. The device is FDA classified as a trocar, and the procedures for which it is used are covered by Medicare and health insurers.

Mr. Tom Donaldson, President of Signet, expressed his gratitude to Dr. Conn and offered staggering statistics. “Our research shows that here in the USA alone we average over 180,000 amputations per year, and all indications are that we may expect more. We know that the mortality rate is well over 50% after one year, not merely from surgery but from the medical results of impaired function. The emotional anguish suffered by these patients is enormous,” says Donaldson. Dr. Conn, who has devoted many years to preventing amputations, noted, “I am very pleased to see this promising device taken to the next level by the Signet team.”

Signet’s Board is determined to make the ConnREAP™ device available to every surgeon in the world by mid-next year. “This is a debilitating disease,” says Mr. Letiziano. “There is no doubt that our ConnREAP™ device will alter the lives of those who are being tormented with making such a frightful decision as amputation. This device will make a difference. We are close to our final design stage and a successful funding offering. Our goal is to start manufacturing and offering the kit for delivery quickly and have patients dancing again. Our stock offering is published and investors are welcome to join us in a meaningful endeavor.”

For additional information contact:
Signet International Holdings, Inc.
Tel. 561-832-2000
Signet International Holdings
Ernest Letiziano