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Metrics, Inc.

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Metrics Inc. Adds Liquids, Creams, Gels to Manufacturing Capabilities

Company's scientists can develop new formulations or accept transfer of existing products

Greenville, NC, April 20, 2013 --( Metrics Inc. now has the ability to produce non-sterile liquids, creams and gels for a broad range of pharmaceutical applications.

The company’s scientists stand prepared to manage the formulation development of new products or the technology transfer of existing products for manufacturing and packaging – as well as provide any necessary laboratory support services.

“The addition of liquids, creams and gels to Metrics’ portfolio of capabilities is just the latest chapter in what has been our tale from the start – delivering demonstrated scientific and operational excellence in response to our clients’ growing and changing needs,” said Phil Hodges, president. “It is an honor to serve our clients in this new way and, hopefully, continue to build upon our long-time relationships based on mutual trust and respect.”

The addition of creams, liquids and gels to Metrics’ existing portfolio of formulation and manufacturing capabilities comes as a result of its recent acquisition by Mayne Pharma Group Limited.

The company’s cream suite can manufacture two- and three-phase suspensions and emulsions, including pastes, creams, lotions and gels. Its two filling lines – which are modular and can be assembled according to product format – and its liquid processing equipment can produce batch sizes ranging from 250 to 2,000 kilograms.

Features of the cream suite include: Mixing turbine with counter-rotating side sweep; recirculation with in-line homogenizer and in-line colloid mill options; steam and chilled water options; a vacuum-charging system; bottom-to-bottom transfers; low-pressure manufacture; calibrated load cells and display systems; side vessels piped directly into vessels with capabilities of 160, 350 and 1,400 liters; clean-in-place systems; and discharge into 1,000 kilograms food-grade pallecons or 200-liter poly-lined drums for transfer to filling lines.

The company’s liquid suite can manufacture bulk liquids, including mouthwash, antiseptics, elixirs and suspensions. A flame-proofed area also is available and suitable for processing flammable liquids. The suite’s four liquid manufacturing vessels produce batch sizes ranging from 350 to 6,000 liters.

Features of the liquid suite include: One-, two- and three-propeller shaft stirrers; calibrated load cells and displays; powder loading options; bottom-to-bottom transfers; recirculation capabilities with filtration, colloid mill and homogenizer options; vacuum-charging system; in-line filtration systems; and discharge into holding containers or piped direct to filling lines.

Metrics Inc. is a full-service global pharmaceutical development and manufacturing organization serving clients worldwide.

The company’s areas of expertise include quality pharmaceutical formulation development; first-time-in-man (FTIM) formulations; clinical trial manufacturing (CTM) for Phase I, II and III trials; and analytical method development and validation services leading to commercial scale manufacturing.

Metrics’ technical capabilities include highly potent, cytotoxic and unstable compounds; Schedule II-V controlled substances; and products with poor bioequivalence – for which we offer an impressive portfolio of advanced proprietary delivery methods.

Our work supports investigational new drug (IND), new drug (NDA) and abbreviated new drug (ANDA) submissions made to worldwide regulatory agencies on behalf of clients ranging from internationally renowned corporations to small virtual companies.

Based in Greenville, N.C., Metrics Inc. proudly operates as a subsidiary of Mayne Pharma Group Limited. To learn more about our company, visit metricsinc dot com. To learn more about Mayne Pharma, visit maynepharma dot com.
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Metrics, Inc.
Karen Stinneford

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