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HRC Fertility Announces 1st Baby Born After Using New PGD Technology for 24-Chromosome Screening and Single Gene Screening for Tay-Sachs

HRC Fertility used a new screening technology called Parental Supportâ„¢ created by Gene Security Network (GSN)

Laguna Hills, CA, May 14, 2011 --( HRC Fertility, the leading fertility clinic on the West Coast, announced today their 1st baby born after using a new preimplantation genetic diagnosis (PGD) technology to enable both 24-chromosome screening and single gene screening for Tay-Sachs. Kira Mae Tabakin was born on March 4th, 2011.

Melanie and Dudley Tabakin had pursued failed assisted reproductive technologies with other doctors for infertility prior to choosing Dr. Daniel Potter at HRC Fertility. Melanie and Dudley were both found to be carriers for Tay-Sachs disease, a lethal condition. Without intervention, there would be a 25% chance that any child they had would be affected by Tay-Sachs and a 50% chance that they would be carriers. Dr. Potter recommended that the couple utilize in vitro fertilization (IVF) with pre-implantation genetic diagnosis (PGD). PGD is a process that allows doctors to test embryos created with IVF for genetic diseases prior to transferring the embryos into the intended mother. Traditional PGD would have allowed the couple to screen their embryos for only Tay-Sachs or another genetic condition.

Dr. Potter recommended utilizing a PGD screening technology called Parental Support™ created by Gene Security Network (GSN) to screen for genetic abnormalities before implantation during an in-vitro fertilization cycle. Parental Support overcomes the technical limitations of previous technologies to provide more comprehensive and accurate testing for patients including single gene testing which the Tabakin’s did for Tay-Sachs. For the first time, using Parental Support, patients can use PGD to accurately look at the complete chromosomal status of their embryos and screen them for genetic diseases at the same time.

“When using a single embryonic cell to do genetic testing, other technologies limit us to looking at a small fraction of the chromosomes. We also had to choose between screening the embryos for abnormalities of chromosomal number like Down syndrome and screening for single gene disorders like Tay-Sachs. With GSN’s Parental Support, we can now do both and with tremendous accuracy. With GSN’s technology, we were able to offer a more comprehensive test to screen for Tay-Sachs for the Tabakin’s,” said Daniel Potter at HRC Fertility. “It is our goal at HRC to assist couples in the best way possible by offering the most advanced technologies and options. We are thrilled that the Tabakin’s were blessed with Kira in March and grateful for their courage in using the new technology. It is not often you get a chance to do something that has never been done before.”

“We are forever grateful to HRC, Dr. Potter and GSN. After numerous attempts with other clinics, Dr. Potter set us on the correct path and recommended Parental Support after we came up positive as carriers of Tay Sachs,” said Melanie Tabakin. “Kira is the joy of our lives and we are so thrilled HRC introduced us to this new technology that allowed us to have a healthy child.”

About Tay-Sachs: Tay-Sachs disease is a deadly disease of the nervous system passed down through families.Tay-Sachs has been classified into infantile, juvenile, and adult forms, depending on the symptoms and when they first appear. Most people with Tay-Sachs have the infantile form. In this form, the nerve damage usually begins while the baby is still in the womb. Symptoms usually appear when the child is 3 to 6 months old. The disease tends to get worse very quickly, and the child usually dies by age 4 or 5.

About GSN and Parental Support: GSN’s proprietary Preimplantation Genetic Screening technology has been published in the leading medical journal Human Reproduction, and is more comprehensive than other existing methods used to detect chromosome abnormalities during in vitro-fertilization (IVF). Parental Support™ can screen 24 chromosomes for abnormalities and can also simultaneously test for single cell genetic diseases. GSN began offering its screening for chromosome abnormalities to IVF clinics in October 2008, and for combined single gene and chromosome screening in early 2010.In both cases, HRC Fertility was one of the first clinics to offer the test. The technology enables fast turnaround of highly accurate test results that can be returned in time for a fresh embryo transfer on the morning of Day 5 during an IVF cycle. Parental Support™ relies on genetic data obtained from samples from both the mother and father. So, knowing specific genetic data from the mother and the father can help test the embryo more reliably.

About HRC Fertility: Since its inception in 1988, HRC Fertility has been one of the largest providers of advanced reproductive care in the United States. HRC has three full-service in vitro fertilization laboratories and seven locations throughout Southern California, with offices in Los Angeles, Orange and Ventura counties. HRC Fertility’s ten physicians have extensive experience in reproductive medicine. For additional information about any of the services HRC Fertility offers, please visit them online at

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CWR & Partners
Kelly Cinelli

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